Dosed 33 participants in the Phase 1/2 INSPIRE DUCHENNE clinical trial as of January 9, 2026; SGT-003 continues to be ...

Dyno Therapeutics, Inc., a genetic technologies company applying artificial intelligence (AI) to solve the grand challenge of in vivo gene delivery, today announced Dyno-yp2, a novel adeno-associated ...

Avista Therapeutics, a preclinical gene therapy company built on deep clinical, computational and gene therapy expertise, today announced the significant expansion of its gene therapy platform.

In a mature, infectious HIV-1 virion, the viral genome is housed within a conical capsid core made up of the viral capsid (CA) protein. During infection, the CA protein interacts with several cellular ...

Assembly and budding of a virus from a membrane microdomain. Viruses have an outer protein shell called a capsid which surrounds the viral nucleic acid. Enveloped viruses, such as HIV, have an ...

For most of his career at Gilead Sciences, medicinal chemist Winston Tse has lived and breathed one thing. While his peers at other companies hopped from project to project, Tse has spent the past ...

Novel capsid technology to enable convenient delivery in the doctor’s office of IKAR-003 for intermediate AMD, designed to prevent progression to sight-threatening disease ...

The capsid of the hepatitis B virus has a very unique structure. It is composed of many monomers which interact to provide flexibility to its structure and function. Hepatitis B virus (HBV) is a ...

Though treatments are available, there is no cure or vaccine from HIV, which impacts about 38 million people worldwide. It's difficult to target the RNA genome of the HIV virus in part because it ...

We performed the first ever simulations of simultaneous capsid assembly and encapsulation of a polymer, we characterized the role of the polymer in this cooperative assembly process and obtained ...