Per- and polyfluoroalkyl substances (PFAS), manmade chemicals that accumulate in the body over time, have been linked to liver disease and cancer, but it is not yet clear how they cause damage.

The liver is one of the most essential organs in the human body, performing critical functions such as detoxifying blood, metabolising nutrients and medications, producing bile, and supporting the ...

If scientists could shrink themselves to microscopic size and take a journey through the human body—like the submarine crew in the 1966 science fiction classic "Fantastic Voyage"—one of their first ...

Human periportal assembloid, showcasing the three key cell types of the liver: portal fibroblasts (magenta), cholangiocytes (green), and hepatocyte nuclei (blue). All cell borders are delineated in ...

While organoids aim to mimic human organs, the liver's repertoire of complex functions – and thus the energy it needs to operate – have made it challenging for researchers to grow organoids that ...

Close-up of a human liver lobule highlighting GLUL (glutamine synthetase) + liver cells surrounding the central vein (grey), with intensity-based pseudocoloring of CD32b expression showing the highest ...

A multidisciplinary team from China has successfully transplanted a gene-modified pig liver into a human recipient diagnosed with brain death. During a 10-day observation period, the porcine liver ...

We’ve reached a new frontier in organ transplantation. In a medical first, scientists announced this week that they successfully kept a genetically modified pig liver functioning inside a human ...