A research team led by the Universitat Autònoma de Barcelona (UAB) has revealed how the genome is reorganized in 3D during ...

Researchers at Karolinska Institutet have demonstrated that it is possible to create early germ cells from preserved testicular tissue of young boys facing cancer therapy.

Although assisted reproductive technologies (ARTs), such as in vitro fertilization (IVF), have had a tremendous impact on treating certain forms of infertility—not all forms of infertility can be ...

Germ cell development begins with the specification of primordial germ cells (PGCs) in the early embryo, which subsequently migrate to the developing gonads and undergo extensive epigenetic ...

Maternal messenger RNAs (mRNAs), located within the cytoplasm of an immature egg, are crucial for jump starting development. Following fertilization, these mRNAs are passed onto the zygote, the first ...

Can fragments of tumor DNA in the blood predict whether chemotherapy will be effective? Researchers at the Princess Máxima Center investigated this question together with experts from Italy and ...

A study conducted by the Molecular Oncology Research Center (CPOM) at Hospital de Amor in Barretos (formerly Barretos Cancer Hospital) in the state of São Paulo, Brazil, has identified possible ...

Non-seminoma is a type of germ-cell testicular cancer. Treatment may include surgery to remove a testicle, lymph node removal, and chemotherapy. Most cases of testicular cancer develop from germ cells ...

Use of CRISPR-KO screening to identify novel genes and pathways potentially contributing to cisplatin resistance in testicular germ cell tumors. Effect of exosome-derived lncRNA on MAL+ CTL apoptosis ...

Tsukuba, Japan—Animal organs are enclosed by a specialized epithelial layer. Epithelial cells typically exhibit apicobasal polarity: their apical surfaces contact other cells or the environment, ...

The development of germ cells encompasses a highly orchestrated series of events that transform pluripotent precursors into mature gametes. Primordial germ cells are specified in the early embryo ...