Alzheimer’s disease has long been the nightmare diagnosis that medicine could slow at best, not stop. Now a wave of ...

The Food and Drug Administration and National Institutes of Health held a joint workshop July 7 on reducing animal testing in research, strikingly announcing that “NIH will no longer seek proposals ...

In recent months, the Food and Drug Administration and National Institutes of Health have announced new initiatives to reduce and replace animal testing in biomedical research. Central to these ...

In the wild, a mouse or rat leads a precarious life. In the city, they dodge traps, poisons, and broom-wielding humans. In the countryside, they face owls, shotguns, and more poison. As Australia’s ...

A new study found that fixing energy balance in the brain reversed symptoms of advanced Alzheimer’s in mice.  Researchers ...

A fundamental challenge in preclinical research is accurately predicting human responses using conventional animal models. Traditional approaches often fail to adequately model human disease, creating ...

For decades, preclinical testing in mice, rats, and nonhuman primates has been a crucial part of drug development, an important although not infallible way to ensure some measure of safety for human ...