CluMPS—Clusters Magnified by Phase Separation—is a fluorescent reporter strategy for detecting protein clusters. It promises to facilitate the visualization of protein clusters that are too small to ...
Chemidroplet is a chemical tool, that fused the BTB-containing domain to the multivalent DNA binding domain (DBD) and intrinsically disordered regions (IDRs) to readily control the LLPS of these ...
The prion protein forms functional condensates that are enriched at cell-cell interfaces. However, long exposure to copper ions/hydrogen peroxide that result in oxidative stress, triggers a ...
Inside cells, RNAs and proteins form tiny, liquid-like droplets called biomolecular condensates. These droplets are essential for organizing cellular life, yet why some RNAs cluster more readily than ...