While researchers are now familiar with how cancer begins—cells mutate and then multiply wildly out of control—it is still uncertain exactly how that mutation starts in the molecules of the cells.

New research is analyzing the role of enzyme Topo II and how its functions may show how cancer mutations are born. Topo II is an essential protein necessary for normal cell division, but it is found ...

Survival after nonmyeloablative versus myeloablative allotransplantation for AML/MDS. Autologous stem cell transplantation (ASCT) as upfront or salvage therapy for noncutaneous T-cell lymphoma (TCL): ...

Topoisomerase II is a key player in both the etiology and treatment of many cancers, including both primary and metastatic diseases. Normally, Topo II creates a transient gate in a DNA duplex by ...

New ARCHITECT plasma pro-gastrin-releasing peptide assay and lung cancer: Implications for diagnosis, follow-up, and prognosis. This is an ASCO Meeting Abstract from the 2015 ASCO Annual Meeting I.