The CB1 receptor is activated by cannabinoids, generated naturally inside the body (endocannabinoids) or exogenously, normally through cannabis or a related synthetic …

The CB1 cannabinoid receptor is a G-protein coupled receptor highly expressed throughout the central nervous system that is a promising target for the treatment of various disorders, …

Jul 23, 2025 · CB1 receptors are specialized proteins found on the surface of cells throughout the human body. They function as receiving antennas, interacting with chemical signals that help …

Cannabinoid receptor type 1 (CB1) is a G-protein-coupled receptor (GPCR) that couples to the inhibitory Gi/o class of G proteins and is predominantly expressed presynaptically in the …

The high-resolution cryo-EM structure of CB1-β-arrestin1 complex offers insights into the distinction of agonists in various transducer-coupled states and reveals the molecular …

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Cannabinoid receptor type 1 (CB 1) receptors are thought to be one of the most widely expressed G αi protein-coupled receptors in the brain.

CB1 receptors are G-protein coupled receptors (GPCRs) abundant in neurons, in which they modulate neurotransmission. The CB1 receptor influence on memory and learning is well …

Feb 26, 2025 · CB1 receptors are a type of G protein-coupled receptor (GPCR) that is widely distributed throughout the central nervous system. They are triggered by cannabinoids, which …

Jul 26, 2025 · Within the brain, CB1 receptors are abundant in areas such as the neocortex, hippocampus, basal ganglia, and cerebellum. Their presence in these regions explains their …