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  1. Clusterin - Wikipedia

    Clusterin is a protein that in humans is encoded by the CLU gene on chromosome 8. [5] CLU is an extracellular molecular chaperone which binds to misfolded proteins in body fluids to …

  2. Structural analyses define the molecular basis of clusterin ... - Nature

    Aug 8, 2025 · Clusterin (apolipoprotein J), a conserved glycoprotein abundant in blood and cerebrospinal fluid, functions as a molecular chaperone and apolipoprotein.

  3. The Ins and Outs of Clusterin: Its Role in Cancer, Eye Diseases and ...

    Clusterin (CLU) is a glycoprotein originally discovered in 1983 in ram testis fluid. Rapidly observed in other tissues, it was initially given various names based on its function in different tissues. In …

  4. Clusterin: structure, function and roles in disease

    Jan 21, 2025 · Clusterin (CLU) is a glycoprotein that exists in various forms in cells, including nuclear, cytoplasmic, and secreted types. The relative molecular weight of CLU varies …

  5. Clusterin: Always protecting. Synthesis, function and potential …

    Feb 1, 2021 · In humans, clusterin is coded by a 16Kb gene localized in chromosome 8p21-p12, that presents 11 exons (two of which are untranslated) of different sizes.

  6. Clusterin Protein: Functions and Role in Disease

    Aug 2, 2025 · Clusterin is present in various tissues and bodily fluids, including blood, cerebrospinal fluid, and numerous organs. Clusterin acts as a molecular chaperone, …

  7. Frontiers | The clusterin connectome: Emerging players in …

    Mar 15, 2023 · Clusterin is involved in lipid transport, cell differentiation, regulation of apoptosis, and clearance of cellular debris, and plays a protective role in ensuring cellular survival. …

  8. Clusterin: structure, function and roles in disease - PubMed

    Jan 21, 2025 · Clusterin (CLU) is a glycoprotein that exists in various forms in cells, including nuclear, cytoplasmic, and secreted types. The relative molecular weight of CLU varies …

  9. Clusterin’s Diverse Functions and Role in Disease

    Jul 29, 2025 · Clusterin is a protein found throughout the body, involved in numerous biological processes. Its widespread presence hints at its diverse roles, making it a subject of ongoing …

  10. The Ins and Outs of Clusterin: Its Role in Cancer, Eye Diseases and ...

    Aug 24, 2023 · Clusterin (CLU) is a glycoprotein originally discovered in 1983 in ram testis fluid. Rapidly observed in other tissues, it was initially given various names based on its function in …