Physical stability of dry powder inhaler formulations - PMC
Various techniques have been employed to produce inhalation drug particles and improve the delivery efficiency of DPI formulations. Physical stability of these DPI formulations is critical to …
A comprehensive overview of dry powder inhalers for pulmonary …
Jun 1, 2023 · The dry powder formulation is composed of hollow porous particles of tobramycin that was developed using Novartis PulmoSphere™ technology. However, the prescribed dose …
Inhalation Dosage Forms: A Focus on Dry Powder Inhalers and
Nov 28, 2023 · In this review, an extensive analysis of dry powder inhalers (DPIs) is offered, focusing on their characteristics, formulation, stability, and manufacturing.
Formulation of Dry Powders for Inhalation Comprising High …
Mar 15, 2022 · Spray-dried formulations of a hydrophobic, crystalline drug, GDC-A, were prepared using the suspension-PulmoSphere™ technology. Increases in drug loading resulted in …
For the dry powder inhaler (DPI), these goals can be met with a suitable powder formulation, an efficient metering system, and a carefully selected device. This review focuses on the DPI …
Formulation and Evaluation of Dry Powder Inhaler - IJRASET
This review focuses on the dry powder inhaler (DPI) formulation and development process. Most DPI formulations consist of micronized drug blended with larger carrier particles, which …
Recent developments in dry powder inhalation (DPI) formulations …
Oct 30, 2023 · In this paper, we discuss the current usage trends and development strategies of dry powder inhalation (DPI) formulations for targeted drug delivery to the lungs.
Design, development, and technical considerations for dry powder ...
May 1, 2024 · Dry powder inhalers (DPI) are one of the convenient and accepted modes of pulmonary drug delivery. Formulation and device design are an integral parts of DPI product …
Inhalable Nanoparticle-based Dry Powder Formulations for …
Among various available devices in aerosol delivery, dry powder inhalers (DPIs) are preferable for delivery of nanoparticles due to their simplicity of use, high portability, and superior long-term …
Early dry powder inhalers were designed for low drug doses in asthma and COPD therapy. Nearly all concepts contained carrier based formulations and lacked efficient dispersion principles.